neurosecretory granules
Membrane-bound vesicles containing hormones and neuropeptides ready for release from nerve terminals.
Full Definition
Neurosecretory granules are specialized organelles found in neuroendocrine cells that store hormones, neuropeptides, and associated proteins until they are released by exocytosis. These dense-core vesicles contain high concentrations of bioactive substances along with processing enzymes and binding proteins. The granules are formed in the Golgi apparatus and transported along axons to nerve terminals, where they await appropriate stimuli for hormone release. The study of neurosecretory granules is essential for understanding hormone storage, processing, and secretion mechanisms in neuroendocrine disorders.
Usage
Usage note: Always use plural form unless referring to a single granule; hyphenate compound modifiers.
In Context
- "Electron microscopy revealed abundant neurosecretory granules in the posterior pituitary nerve terminals." — Research paper
- "The immunohistochemical stain highlighted neurosecretory granules containing growth hormone." — Pathology report