magnetization transfer ratio
Quantitative measure of macromolecular content derived from magnetization transfer imaging sequences.
Full Definition
Magnetization transfer ratio (MTR) is a quantitative metric derived from magnetization transfer imaging that reflects the macromolecular content and structural integrity of brain tissue. MTR values are calculated from images acquired with and without off-resonance saturation pulses, providing insight into myelin content, protein density, and tissue microstructure. Reduced MTR values indicate loss of macromolecular organization, making this technique valuable for detecting subtle white matter pathology in neurological diseases.
Usage
Usage note: Often abbreviated as MTR; distinguish from magnetization transfer imaging, which is the technique rather than the measurement.
In Context
- "MTR analysis revealed decreased values in normal-appearing white matter." — Multiple sclerosis study
- "Histogram analysis showed a leftward shift in magnetization transfer ratio distribution." — Quantitative imaging report