neuroinflammation
Inflammatory response within the central nervous system involving activation of resident immune cells and peripheral immune infiltration.
Full Definition
Neuroinflammation refers to the inflammatory response that occurs within the central nervous system, characterized by the activation of resident immune cells such as microglia and astrocytes, as well as infiltration of peripheral immune cells. This process involves the release of pro-inflammatory cytokines, chemokines, and other inflammatory mediators. While neuroinflammation can be a protective response to injury or infection, chronic neuroinflammation is associated with various neurodegenerative and autoimmune neurological diseases.
Usage
Usage note: Avoid hyphenation; write as one word. Distinguish from general inflammation affecting nervous tissue.
In Context
- "Chronic neuroinflammation contributes to disease progression in multiple sclerosis patients." — Clinical research paper
- "Anti-inflammatory therapies aim to modulate neuroinflammation while preserving beneficial immune responses." — Treatment protocol