thymectomy
Pronunciation: thy-MEK-toh-mee
Surgical removal of the thymus gland, performed as treatment for myasthenia gravis, particularly in patients with thymoma.
Full Definition
Thymectomy is the surgical removal of the thymus gland, most commonly performed as treatment for myasthenia gravis. The procedure is strongly recommended for patients with thymoma and is considered beneficial for non-thymomatous myasthenia gravis patients, particularly those under 60 years with generalized disease. The thymus plays a crucial role in the autoimmune pathogenesis of myasthenia gravis, containing acetylcholine receptors and serving as a site of antibody production. Surgical approaches include transsternal, transcervical, and minimally invasive techniques including thoracoscopic and robotic methods. Benefits may include reduced medication requirements, improved symptoms, and increased likelihood of remission, though effects may take months to years to manifest fully.
Usage
Usage note: Distinguish clearly from thyroidectomy; specify surgical approach when relevant.
In Context
- "Thymectomy was recommended given the patient's young age and generalized myasthenia gravis." — Surgical consultation note
- "The patient showed significant improvement in myasthenic symptoms six months following thymectomy." — Post-operative follow-up