DIPG
Pronunciation: D-I-P-G
Also written as: DIPG — Diffuse Intrinsic Pontine Glioma
An aggressive brainstem tumor primarily affecting children with poor prognosis and limited treatment options.
Full Definition
Diffuse intrinsic pontine glioma is a high-grade brainstem tumor that occurs predominantly in children aged 5-10 years. These tumors infiltrate the pons diffusely, making surgical resection impossible due to the critical neurological structures involved. DIPG typically presents with cranial nerve palsies, ataxia, and pyramidal tract signs. The diagnosis is usually made based on characteristic MRI findings without tissue confirmation. Despite radiation therapy, the median survival remains approximately 9-12 months, making DIPG one of the most challenging pediatric brain tumors.
Usage
Usage note: Spell out on first use in family communication documents.
In Context
- "The 7-year-old patient presented with classic DIPG symptoms including diplopia and gait ataxia." — Pediatric oncology consultation
- "MRI revealed typical DIPG characteristics with diffuse T2 hyperintensity expanding the pons." — Radiology interpretation