glioblastoma multiforme
Pronunciation: gly-oh-blas-TOH-mah mul-tih-FOR-may
The most aggressive form of primary brain tumor, requiring precise terminology in clinical documentation.
Full Definition
Glioblastoma multiforme (GBM) is a Grade IV astrocytoma representing the most malignant form of primary brain tumor. It arises from glial cells and is characterized by rapid growth, invasiveness, and poor prognosis. The term 'multiforme' refers to the varied histological appearance of the tumor. In editorial contexts, this term must be distinguished from other gliomas and requires consistent capitalization practices in medical reports.
Usage
Usage note: Always use the full term in formal reports; GBM acceptable in clinical notes after first use.
In Context
- "The patient was diagnosed with glioblastoma multiforme in the right temporal lobe." — Pathology report
- "Surgical resection remains the primary treatment for glioblastoma multiforme when feasible." — Treatment protocol