posterior fossa syndrome
Also written as: PFS
A postoperative complication following posterior fossa surgery characterized by mutism, ataxia, and behavioral changes.
Full Definition
Posterior fossa syndrome is a well-recognized complication that can occur following surgical resection of posterior fossa tumors, particularly in pediatric patients. The syndrome is characterized by a triad of transient mutism (inability to speak), truncal ataxia, and behavioral/emotional changes including irritability, apathy, or mood lability. The exact etiology remains unclear but may involve damage to cerebellar-cerebral connections or brainstem structures. While often temporary, recovery can be prolonged and incomplete in some cases. Risk factors include younger age, larger tumor size, and proximity to midline structures. Early recognition and supportive care including speech therapy are important for optimal outcomes.
Usage
Usage note: More commonly observed in pediatric patients undergoing midline posterior fossa surgery.
In Context
- "The 6-year-old developed posterior fossa syndrome following medulloepithelioma resection, with gradual speech recovery over 8 weeks." — Postoperative complication report
- "Parents were counseled about the risk of posterior fossa syndrome before the cerebellar tumor surgery." — Informed consent discussion