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Advanced Technical IVT

demographic stratification

The practice of applying different cutoff values based on infant characteristics such as birth weight or gestational age.

Full Definition

Demographic stratification involves establishing distinct referral criteria and cutoff values for different subpopulations of screened infants, such as term versus preterm babies, or different birth weight categories. This approach recognizes that physiological and analytical parameters vary systematically across demographic groups, allowing optimization of screening performance for each population while reducing inappropriate referrals and maintaining sensitivity for disease detection.

Usage

Usage note: Specify the demographic variables used when describing stratification approaches.

In Context

  • "Demographic stratification by gestational age reduced false positive rates for 17-OHP screening by 35%." — Research publication
  • "The program implemented demographic stratification after observing significant differences in analyte distributions." — Program implementation report

Also known as

population-specific cutoffs stratified analysis

Contrasted with

universal cutoffs

Don't confuse with

risk stratification demographic analysis

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