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salt-wasting crisis
Life-threatening emergency in CAH where infants lose sodium and become dehydrated and hypotensive.
Full Definition
A salt-wasting crisis is a potentially fatal complication of congenital adrenal hyperplasia (CAH) characterized by severe sodium loss, dehydration, hyperkalemia, and circulatory collapse. This emergency typically occurs in the first few weeks of life when aldosterone deficiency prevents normal sodium retention. Early detection through newborn screening is critical because salt-wasting crises can develop rapidly and may be fatal if not promptly treated with IV fluids, electrolyte replacement, and corticosteroid therapy.
Usage
Usage note: Hyphenate 'salt-wasting' when used as a compound adjective.
In Context
- "Prompt newborn screening follow-up prevented a potentially fatal salt-wasting crisis." — Case report
- "Parents were educated about signs of salt-wasting crisis and emergency treatment protocols." — Discharge planning note
Also known as
adrenal crisis
salt-losing crisis
Don't confuse with
dehydration
shock
sepsis