cordocentesis

Full Definition

Cordocentesis, also known as percutaneous umbilical blood sampling (PUBS), is an invasive prenatal procedure performed under ultrasound guidance to obtain foetal blood from the umbilical cord vessels. Typically performed after 18 weeks gestation, it allows for rapid karyotyping, assessment of foetal anaemia, infection status, and acid-base balance. The procedure carries a small risk of pregnancy loss and is reserved for specific clinical indications.

Usage

Usage note: PUBS is the more commonly used abbreviation in clinical practice.

In Context

• "Cordocentesis was performed to assess foetal haemoglobin levels in suspected anaemia." — Procedure report
• "The couple opted for cordocentesis after abnormal ultrasound findings at 20 weeks." — Genetic counselling note