endometrial hyperplasia
Abnormal thickening of the uterine lining that may progress to endometrial cancer if untreated.
Full Definition
Endometrial hyperplasia represents excessive proliferation of endometrial glands and stroma, typically resulting from unopposed estrogen stimulation. This condition is classified as simple or complex, with or without atypia, based on architectural complexity and cellular abnormalities. Atypical hyperplasia carries significant malignant potential and requires aggressive management. The condition commonly presents with abnormal uterine bleeding and is diagnosed through endometrial biopsy or curettage.
Usage
Usage note: Always specify the subtype (simple/complex, with/without atypia) in clinical documentation.
In Context
- "The pathology report confirmed complex endometrial hyperplasia with atypia, requiring hysterectomy consultation." — Histopathology report
- "Progestin therapy was initiated to treat the simple endometrial hyperplasia without atypia." — Treatment plan