Professional
Technical
IVT
fetal fibronectin
A glycoprotein found in cervical and vaginal secretions that serves as a biomarker for predicting preterm birth risk.
Full Definition
Fetal fibronectin (fFN) is a glycoprotein normally present at the interface between the chorion and decidua during early pregnancy. Its detection in cervical or vaginal secretions after 22 weeks gestation indicates disruption of the maternal-fetal interface and is associated with increased risk of preterm delivery within 7-14 days. The test is primarily used as a negative predictor - a negative result provides strong reassurance that delivery is unlikely to occur within the next two weeks.
Usage
Usage note: Often abbreviated as fFN in clinical notes; ensure correct spelling of 'fibronectin' not 'fibronectin'.
In Context
- "The fetal fibronectin test was negative, providing reassurance that preterm delivery was unlikely." — Obstetric assessment report
- "Elevated fetal fibronectin levels prompted immediate corticosteroid administration." — High-risk pregnancy documentation
Also known as
fFN
Don't confuse with
fibrinogen
ferritin