pseudohypopyon
Pronunciation: SOO-doh-HY-poh-pyon
Layered white material in the anterior chamber that mimics hypopyon but consists of tumor cells rather than inflammatory debris.
Full Definition
Pseudohypopyon is a distinctive clinical finding in intraocular malignancies, particularly retinoblastoma and lymphoma, where tumor cells settle in the inferior anterior chamber creating a white layered appearance similar to infectious hypopyon. Unlike true hypopyon which consists of inflammatory cells and debris, pseudohypopyon is composed of malignant cells that have gained access to the anterior chamber through tumor invasion or cellular shedding. This finding is highly suggestive of intraocular malignancy and requires immediate oncological evaluation. The presence of pseudohypopyon in retinoblastoma indicates advanced disease with potential for anterior chamber seeding and increased risk of extraocular extension.
Usage
Usage note: The prefix 'pseudo-' emphasizes the non-inflammatory nature despite similar appearance.
In Context
- "The presence of pseudohypopyon in this pediatric patient raised immediate concern for retinoblastoma." — Emergency consultation note
- "Cytological analysis of the anterior chamber tap confirmed malignant cells in the pseudohypopyon." — Laboratory report