tumor doubling time
The time required for a tumor to double in volume, used to assess growth rate and guide treatment decisions.
Full Definition
Tumor doubling time is a critical parameter in ocular oncology that quantifies the rate of tumor growth by measuring the time required for the lesion to double in volume. For uveal melanomas, doubling times typically range from several months to years, with faster growth rates generally indicating more aggressive tumors requiring immediate intervention. The measurement is calculated using serial imaging studies, most commonly A-scan ultrasonography, and requires precise documentation of tumor dimensions over time. Tumors with doubling times less than one year are typically considered for active treatment, while those with longer doubling times may be candidates for observation.
Usage
Usage note: Should be calculated from volume measurements, not linear dimensions, for accuracy.
In Context
- "The choroidal lesion demonstrated a tumor doubling time of eight months, prompting immediate treatment." — Clinical assessment note
- "Serial ultrasonography revealed a tumor doubling time exceeding two years, supporting continued observation." — Surveillance report