limbus
Pronunciation: lim-bus
Junction between the cornea and sclera, important for surgical anatomy and stem cells.
Full Definition
The limbus is the transitional zone between the clear cornea and the white sclera, forming a circular junction around the cornea. This region is anatomically and functionally significant as it contains corneal stem cells in the palisades of Vogt, which are crucial for corneal epithelial renewal. The limbus also serves as an important surgical landmark for many ocular procedures. Limbal stem cell deficiency can lead to corneal surface disorders, while limbal anatomy guides incision placement in procedures such as cataract surgery, corneal transplants, and glaucoma surgery. The limbus is approximately 1.5-2mm wide and shows variation in pigmentation among individuals.
Usage
Usage note: Specify anatomical quadrant when describing limbal pathology or surgical approaches.
In Context
- "The corneal incision was made 2mm posterior to the limbus for optimal wound architecture." — Operative report
- "Limbal stem cell deficiency was evident with corneal pannus extending across the visual axis." — Clinical examination