Zonulopathy
Pronunciation: ZOH-nyoo-lop-uh-thee
A condition affecting the zonular fibers that support the crystalline lens, potentially compromising lens stability during surgery.
Full Definition
Zonulopathy refers to weakness, damage, or abnormality of the zonular fibers (also called zonules of Zinn) that suspend the crystalline lens within the eye. This condition can be congenital or acquired, often associated with conditions like pseudoexfoliation syndrome, Marfan syndrome, or trauma. In surgical contexts, zonulopathy presents significant challenges during cataract extraction as weakened zonules may lead to lens instability, capsular bag deformation, or vitreous loss. Surgeons must modify their technique when zonulopathy is present, often requiring capsular tension rings or other support devices to maintain lens capsule integrity during phacoemulsification.
Usage
Usage note: Often hyphenated in compound forms (zonulopathy-related complications). Distinguish from zonulolysis, which refers to deliberate surgical division of zonules.
In Context
- "Preoperative assessment revealed significant zonulopathy secondary to pseudoexfoliation, requiring modified surgical approach." — Surgical planning note
- "The patient's zonulopathy was managed intraoperatively with insertion of a capsular tension ring to stabilize the capsular bag." — Operative report