gross total resection
Also written as: GTR — Gross Total Resection
Complete surgical removal of all visible tumor tissue, though microscopic disease may remain.
Full Definition
Gross total resection (GTR) refers to the surgical achievement of removing all macroscopically visible tumor tissue during the operative procedure. While the surgeon has removed all tumor that can be seen with the naked eye, microscopic tumor cells may still remain at the resection site. This term is commonly used in neurosurgery and other oncologic specialties where complete resection may be limited by anatomical constraints. GTR is distinguished from complete resection, which implies both macroscopic and microscopic tumor clearance.
Usage
Usage note: Distinguish from 'complete resection' which implies microscopic clearance.
In Context
- "Gross total resection was achieved for the glioblastoma with no visible residual tumor on immediate postoperative imaging." — neurosurgical operative report
- "The goal of gross total resection was balanced against preservation of neurological function." — surgical planning note