Intermediate
Technical
IVT
positive margin
Presence of tumor cells at the edge of surgically resected tissue, indicating incomplete excision.
Full Definition
A positive margin occurs when cancer cells are found at the inked edge of the surgical specimen, indicating that tumor extends to the boundary of the resection. This finding suggests that tumor cells may remain in the patient after surgery, increasing the risk of local recurrence. Positive margins may necessitate additional surgery (re-excision), adjuvant radiation therapy, or changes in systemic treatment plans. The clinical significance varies by tumor type, with some cancers being more tolerant of positive margins than others.
Usage
Usage note: Specify the location and extent of margin involvement when documenting.
In Context
- "The pathology report indicated a positive margin at the deep aspect of the resection specimen." — pathology report
- "Re-excision was recommended due to positive margins on the initial lumpectomy specimen." — surgical consultation note
Also known as
involved margin
close margin
Contrasted with
negative margin
clear margin
Don't confuse with
close margin
narrow margin