second-look surgery
Planned surgical re-exploration performed after initial treatment to assess treatment response and detect residual disease.
Full Definition
Second-look surgery is a planned surgical procedure performed after completion of initial therapy (surgery, chemotherapy, or radiation) to evaluate treatment response, detect residual or recurrent disease, and potentially provide additional therapeutic intervention. This approach is most commonly employed in ovarian cancer management where systematic exploration and tissue sampling can identify microscopic residual disease not detectable by imaging. The procedure may involve peritoneal washings, multiple biopsies from previous disease sites, and resection of any visible abnormalities. Results influence decisions about continuation or modification of systemic therapy. The concept differs from emergency or symptomatic re-operation as it is pre-planned and performed in asymptomatic patients.
Usage
Usage note: Distinguish from emergency re-operation or completion surgery; specify the indication and planned timing.
In Context
- "Second-look surgery revealed no evidence of residual ovarian carcinoma after six cycles of chemotherapy." — Operative report
- "The role of second-look surgery in ovarian cancer management remains controversial in current practice." — Clinical guideline