Whipple procedure
Pronunciation: WHIP-uhl
Complex pancreaticoduodenectomy involving removal of the pancreatic head, duodenum, gallbladder, and distal bile duct, primarily for pancreatic and periampullary tumors.
Full Definition
The Whipple procedure, formally known as pancreaticoduodenectomy, is one of the most complex operations in oncologic surgery, typically performed for cancers of the pancreatic head, ampulla of Vater, distal bile duct, or duodenum. The procedure involves removal of the pancreatic head, entire duodenum, gallbladder, distal bile duct, and sometimes a portion of the stomach. Following resection, complex reconstructions are required to restore digestive continuity, including pancreaticojejunostomy, hepaticojejunostomy, and gastrojejunostomy. Named after American surgeon Allen Whipple, this procedure carries significant morbidity and mortality risks but offers the only potential cure for pancreatic adenocarcinoma.
Usage
Usage note: Capitalize 'Whipple' as it's an eponym; may be abbreviated as PD in clinical notes.
In Context
- "The patient underwent a successful Whipple procedure with negative margins achieved." — Operative report
- "Preoperative imaging suggested the patient would be a candidate for the Whipple procedure." — Multidisciplinary conference note