Oncology Informatics Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
COSMIC COSMIC
The Catalogue of Somatic Mutations in Cancer, a comprehensive database of cancer-associated genetic variants.
actionable mutation
A genetic alteration for which targeted therapy options or clinical trials are available.
adverse event
Unfavorable medical occurrence in a cancer patient during treatment, requiring systematic documentation and severity gra...
AJCC staging
American Joint Committee on Cancer staging system - the gold standard for cancer staging and prognosis.
AJCC staging algorithm
Automated computational logic that determines cancer stage classification based on tumor characteristics and anatomical...
allelic fraction
The proportion of sequencing reads containing a variant allele at a specific genomic position in tumor tissue.
biomarker
Measurable biological indicator used to assess cancer diagnosis, prognosis, or treatment response in clinical informatic...
cancer genome atlas
A comprehensive database containing genomic, transcriptomic, and clinical data from thousands of cancer patients.
cancer imaging informatics
Specialized field applying computational methods to cancer imaging data for enhanced diagnosis, treatment planning, and...
cancer informatics pipeline
A structured workflow that processes cancer data from raw input through analysis to clinical insights.
cancer informatics specialist
A healthcare informatics professional with specialized expertise in managing, analyzing, and interpreting cancer-related...
cancer pathway analytics
Data analysis methods that examine patient treatment journeys and care patterns across the cancer continuum from diagnos...
cancer pathway informatics
Computational approach to modeling, analyzing, and optimizing cancer care delivery workflows and clinical decision pathw...
cancer quality measure repository
Centralized database containing standardized metrics and algorithms for assessing cancer care quality across healthcare...
cancer registry abstractor
A healthcare professional trained to systematically extract and code cancer-related data from medical records for popula...
cancer surveillance informatics
Computational discipline focused on systematic collection, analysis, and reporting of cancer incidence and outcome data...
CAP checklist
Standardized reporting templates developed by the College of American Pathologists to ensure comprehensive and consisten...
case ascertainment
The systematic process of identifying and confirming cancer cases within a defined population for inclusion in cancer su...
CDASH
Clinical Data Acquisition Standards Harmonization - CDISC standard for case report form design in oncology trials.
CDISC ODM
Clinical Data Interchange Standards Consortium Operational Data Model, a vendor-neutral format for exchanging and archiv...
CDSS oncology module
Specialized clinical decision support component that provides treatment recommendations and drug interaction alerts spec...
chemotherapy order verification system
Specialized software platform that validates cancer treatment orders against safety parameters, dosing protocols, and pa...
circulating tumor DNA
Cell-free DNA fragments shed by tumors into the bloodstream, detectable through liquid biopsy techniques.
clinical data abstraction
Systematic process of extracting structured oncology data elements from medical records for research, registry reporting...
clinical data harmonization
Process of standardizing data elements, terminologies, and formats across different oncology systems to enable consisten...