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Oncology Informatics Glossary

100 terms total — 24 showing — Last updated 15 Sep 2026

COSMIC COSMIC

Intermediate Technical IVT

The Catalogue of Somatic Mutations in Cancer, a comprehensive database of cancer-associated genetic variants.

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actionable mutation

Intermediate Technical IVT

A genetic alteration for which targeted therapy options or clinical trials are available.

Technical Term Full entry →

adverse event

Intermediate Technical IVT

Unfavorable medical occurrence in a cancer patient during treatment, requiring systematic documentation and severity gra...

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AJCC staging

Intermediate Technical IVT

American Joint Committee on Cancer staging system - the gold standard for cancer staging and prognosis.

Technical Term Full entry →

AJCC staging algorithm

Professional Technical IVT

Automated computational logic that determines cancer stage classification based on tumor characteristics and anatomical...

Technical Term Full entry →

allelic fraction

Professional Technical IVT

The proportion of sequencing reads containing a variant allele at a specific genomic position in tumor tissue.

Technical Term Full entry →

biomarker

Intermediate Technical IVT

Measurable biological indicator used to assess cancer diagnosis, prognosis, or treatment response in clinical informatic...

Technical Term Full entry →

cancer genome atlas

Intermediate Technical IVT

A comprehensive database containing genomic, transcriptomic, and clinical data from thousands of cancer patients.

Technical Term Full entry →

cancer imaging informatics

Professional Technical IVT

Specialized field applying computational methods to cancer imaging data for enhanced diagnosis, treatment planning, and...

Technical Term Full entry →

cancer informatics pipeline

Advanced Technical IVT

A structured workflow that processes cancer data from raw input through analysis to clinical insights.

Technical Term Full entry →

cancer informatics specialist

Intermediate Formal IVT

A healthcare informatics professional with specialized expertise in managing, analyzing, and interpreting cancer-related...

Technical Term Full entry →

cancer pathway analytics

Advanced Technical IVT

Data analysis methods that examine patient treatment journeys and care patterns across the cancer continuum from diagnos...

Technical Term Full entry →

cancer pathway informatics

Professional Technical IVT

Computational approach to modeling, analyzing, and optimizing cancer care delivery workflows and clinical decision pathw...

Technical Term Full entry →

cancer quality measure repository

Professional Technical IVT

Centralized database containing standardized metrics and algorithms for assessing cancer care quality across healthcare...

Technical Term Full entry →

cancer registry abstractor

Intermediate Technical IVT

A healthcare professional trained to systematically extract and code cancer-related data from medical records for popula...

Technical Term Full entry →

cancer surveillance informatics

Professional Technical IVT

Computational discipline focused on systematic collection, analysis, and reporting of cancer incidence and outcome data...

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CAP checklist

Intermediate Technical IVT

Standardized reporting templates developed by the College of American Pathologists to ensure comprehensive and consisten...

Document Type Full entry →

case ascertainment

Advanced Technical IVT

The systematic process of identifying and confirming cancer cases within a defined population for inclusion in cancer su...

Technical Term Full entry →

CDASH

Professional Technical IVT

Clinical Data Acquisition Standards Harmonization - CDISC standard for case report form design in oncology trials.

Technical Term Full entry →

CDISC ODM

Advanced Technical IVT

Clinical Data Interchange Standards Consortium Operational Data Model, a vendor-neutral format for exchanging and archiv...

Technical Term Full entry →

CDSS oncology module

Professional Technical IVT

Specialized clinical decision support component that provides treatment recommendations and drug interaction alerts spec...

Technical Term Full entry →

chemotherapy order verification system

Professional Technical IVT

Specialized software platform that validates cancer treatment orders against safety parameters, dosing protocols, and pa...

Technical Term Full entry →

circulating tumor DNA

Professional Technical IVT

Cell-free DNA fragments shed by tumors into the bloodstream, detectable through liquid biopsy techniques.

Technical Term Full entry →

clinical data abstraction

Intermediate Technical IVT

Systematic process of extracting structured oncology data elements from medical records for research, registry reporting...

Technical Term Full entry →

clinical data harmonization

Professional Technical IVT

Process of standardizing data elements, terminologies, and formats across different oncology systems to enable consisten...

Technical Term Full entry →
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