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Oncology Informatics Glossary

100 terms total — 24 showing — Last updated 15 Sep 2026

COSMIC COSMIC

Intermediate Technical IVT

The Catalogue of Somatic Mutations in Cancer, a comprehensive database of cancer-associated genetic variants.

Showing 25–48 of 100

clinical data lake

Advanced Technical IVT

Large-scale storage repository that holds vast amounts of structured and unstructured cancer-related data in its native...

Technical Term Full entry →

clinical data management system

Intermediate Technical IVT

Software platform designed to collect, manage, and validate clinical trial data according to regulatory standards.

Technical Term Full entry →

clinical data warehouse

Advanced Technical IVT

A centralized repository that integrates clinical data from multiple healthcare systems and sources to support cancer re...

Technical Term Full entry →

clinical decision support

Intermediate Technical IVT

Health information technology that provides clinicians with cancer-specific assessments and evidence-based recommendatio...

Technical Term Full entry →

clinical trial matching

Intermediate Technical IVT

The process of systematically identifying and connecting cancer patients with appropriate research studies based on thei...

Technical Term Full entry →

clinical variant classification

Professional Technical IVT

The systematic assignment of clinical significance levels to genetic variants based on evidence criteria.

Technical Term Full entry →

CoC standards

Professional Technical IVT

Commission on Cancer accreditation standards for hospital cancer programs and registry operations.

Document Type Full entry →

companion diagnostic

Intermediate Technical IVT

An FDA-approved test required to identify patients eligible for specific targeted cancer therapies.

Technical Term Full entry →

complete response

Intermediate Technical IVT

Disappearance of all detectable disease following cancer treatment, as defined by specific imaging and clinical criteria...

Technical Term Full entry →

copy number variation

Advanced Technical IVT

Genomic alterations involving the duplication or deletion of DNA segments in cancer cells.

Technical Term Full entry →

COSMIC

Intermediate Technical IVT

The Catalogue of Somatic Mutations in Cancer, a comprehensive database of cancer-associated genetic variants.

Technical Term Full entry →

CTCAE

Intermediate Technical IVT

Common Terminology Criteria for Adverse Events - NCI standard for grading adverse events in cancer clinical trials.

Technical Term Full entry →

CTMS

Intermediate Technical IVT

Clinical Trial Management System used to manage the operational aspects of clinical trials including patient enrollment,...

Technical Term Full entry →

DICOM

Intermediate Technical IVT

International standard for medical imaging data storage, transmission, and display, essential for oncology imaging workf...

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disease-free survival

Intermediate Technical IVT

Time from treatment completion or surgical resection until cancer recurrence or death, commonly used in adjuvant therapy...

Technical Term Full entry →

ECOG performance status

Intermediate Technical IVT

Standardized scale from 0-5 measuring a cancer patient's functional capacity and ability to perform daily activities.

Technical Term Full entry →

eCRF

Intermediate Technical IVT

Electronic Case Report Form, a digital data collection instrument used in clinical trials to capture patient information...

Document Type Full entry →

ePRO

Intermediate Technical IVT

Electronic patient-reported outcome tools that capture symptoms, quality of life, and functional status directly from ca...

Technical Term Full entry →

FAIR data principles

Professional Technical IVT

Guidelines for making scientific data Findable, Accessible, Interoperable, and Reusable, particularly important in oncol...

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federated learning

Advanced Technical IVT

Machine learning approach that enables model training across distributed datasets without centralizing patient data, imp...

Technical Term Full entry →

genomic sequencing panel

Advanced Technical IVT

Targeted genetic testing that analyzes multiple cancer-related genes simultaneously to guide precision oncology treatmen...

Technical Term Full entry →

germline variant

Intermediate Technical IVT

A genetic variation present in inherited DNA from parents, found in all cells of the body.

Technical Term Full entry →

HL7 FHIR

Advanced Technical IVT

Health Level Seven Fast Healthcare Interoperability Resources - a standard for health information exchange in oncology s...

Technical Term Full entry →

hotspot mutation

Intermediate Technical IVT

A genetic alteration occurring at a genomic position with high mutation frequency across multiple cancer types or patien...

Technical Term Full entry →
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