moth-eaten pattern
Radiographic appearance of aggressive bone destruction with irregular, permeative margins suggesting malignancy.
Full Definition
The moth-eaten pattern describes a characteristic radiographic appearance of bone destruction where multiple small, irregular radiolucent areas create an appearance resembling fabric damaged by moths. This pattern indicates aggressive, rapidly growing lesions that destroy bone faster than reactive bone formation can occur. The margins are ill-defined and permeative, lacking the sharp borders seen in benign lesions. This radiographic sign is highly suggestive of malignant bone tumors, particularly high-grade sarcomas, and warrants immediate oncological evaluation and tissue diagnosis.
Usage
Usage note: Use to describe radiographic patterns, not histological findings.
In Context
- "Plain radiographs demonstrated a moth-eaten pattern of destruction in the proximal tibia, concerning for malignancy." — Radiology report
- "The moth-eaten appearance on imaging prompted urgent biopsy and oncology referral." — Emergency department note