oncological safety margin
Minimum distance of normal tissue that must surround a resected tumor to ensure complete removal and minimize recurrence risk.
Full Definition
Oncological safety margin represents the width of normal tissue that must be maintained around a tumor during surgical resection to achieve adequate local control. These margins are typically measured in centimeters and vary based on tumor type, grade, and location. High-grade sarcomas generally require wider margins (1-2 cm) compared to low-grade lesions. The margin is measured from the tumor edge to the resection plane and must be maintained in all directions. Positive or close margins (<1 mm) significantly increase local recurrence rates and may require re-excision or adjuvant radiation therapy.
Usage
Usage note: Specify the actual margin width when known, as adequacy varies by tumor type.
In Context
- "Histopathology confirmed negative oncological safety margins throughout the specimen." — Pathology report
- "The proximity to neurovascular structures compromised the achievable oncological safety margin." — Surgical planning note