Advanced
Technical
IVT
skip metastasis
Tumor deposits found in the same bone as the primary tumor but separated by normal tissue, indicating more aggressive disease requiring extended resection margins.
Full Definition
Skip metastasis refers to discontinuous tumor foci within the same bone as the primary lesion, separated by apparently normal bone tissue. This finding significantly alters surgical planning, often necessitating more extensive resection or amputation rather than limb salvage. Skip metastases are most commonly seen in osteosarcoma and represent a poor prognostic factor. Advanced imaging, particularly MRI, is essential for detection, as these lesions may not be apparent on plain radiographs.
Usage
Usage note: Not to be confused with distant metastases or separate primary tumors.
In Context
- "MRI demonstrated skip metastasis in the proximal femur, contraindicated limb salvage surgery." — Radiology report
- "The presence of skip metastasis significantly worsened the patient's prognosis." — Oncology consultation
Also known as
discontinuous tumor foci
satellite tumor deposits
Contrasted with
continuous tumor extension
Don't confuse with
satellite lesion
multifocal disease