necrotizing enterocolitis
A serious gastrointestinal condition primarily affecting premature infants, characterized by inflammation and death of intestinal tissue.
Full Definition
Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency that predominantly affects premature infants in the NICU and PICU. The condition involves inflammation and necrosis of the intestinal wall, potentially leading to perforation, sepsis, and death. Risk factors include prematurity, formula feeding, and compromised intestinal blood flow. Early recognition is critical as the condition can progress rapidly from feeding intolerance to full-blown septic shock requiring immediate surgical intervention.
Usage
Usage note: Always spell out on first use, then abbreviate as NEC. Critical to distinguish from other neonatal gastrointestinal emergencies.
In Context
- "The infant developed signs consistent with necrotizing enterocolitis, including abdominal distension and bloody stools." — PICU progress note
- "Surgical consultation was urgently requested for suspected NEC with pneumoperitoneum." — Emergency department report