café-au-lait macule
Pronunciation: ka-FAY-oh-LAY ma-KYOOL
A flat, coffee-colored birthmark that may be isolated or associated with genetic syndromes when multiple lesions are present.
Full Definition
Café-au-lait macules are benign, uniformly pigmented macules that can occur anywhere on the body. While one or two isolated lesions are common and benign, the presence of six or more café-au-lait macules measuring greater than 5mm in prepubertal children or greater than 15mm in postpubertal individuals may indicate neurofibromatosis type 1. Accurate documentation of the number, size, and distribution of these lesions is crucial for clinical assessment and genetic counseling. The term derives from French, meaning 'coffee with milk,' describing the characteristic light brown coloration.
Usage
Usage note: Maintain hyphenation and accent marks when possible; include measurements for clinical significance.
In Context
- "Seven café-au-lait macules greater than 5mm noted, prompting referral to genetics for neurofibromatosis evaluation." — Clinical assessment note
- "Solitary café-au-lait macule on left shoulder measuring 8mm, likely benign isolated finding." — Physical examination