LCH
Pronunciation: spell out: L-C-H
Also written as: LCH — Langerhans cell histiocytosis
Abbreviation for Langerhans cell histiocytosis; a clonal Langerhans-cell proliferative disorder with characteristic cutaneous and systemic presentations in children.
Full Definition
LCH is the universally accepted abbreviation for Langerhans cell histiocytosis in haematology, oncology, and dermatology literature. It should be defined at first use and is appropriate in subsequent mentions within clinical notes, review articles, and trial protocols. Editors should be alert to the risk of confusion with other histiocytic disorders (e.g., Erdheim–Chester disease, juvenile xanthogranuloma) in pediatric oncology documents, and should ensure the full form precedes any abbreviation at first mention.
Usage
Usage note: Always expand on first use. Do not use as a stand-alone term without prior definition in any formal document.
In Context
- "LCH was confirmed on biopsy in three of the five patients; the remaining two were diagnosed with juvenile xanthogranuloma." — Pediatric dermatology audit report
- "Authors should expand LCH to 'Langerhans cell histiocytosis' on first use in the abstract and again in the main text." — Journal style guide instruction