hypothyroidism
Pronunciation: HIGH-po-THIGH-roid-ism
Thyroid hormone deficiency that can significantly impact growth and development in children.
Full Definition
A condition characterized by insufficient production of thyroid hormones (T4 and T3) by the thyroid gland, which can have profound effects on growth and development in pediatric patients. In children, hypothyroidism may be congenital (present from birth) or acquired. Untreated hypothyroidism leads to growth retardation, delayed bone age, delayed puberty, and cognitive impairment. Early detection through newborn screening and prompt treatment with levothyroxine replacement therapy can prevent most adverse outcomes. Regular monitoring of thyroid function and growth parameters is essential in affected children.
Usage
Usage note: Distinguish between congenital and acquired forms in clinical documentation.
In Context
- "Congenital hypothyroidism was detected on newborn screening with an elevated TSH level." — Newborn screening result
- "The child's growth failure was attributed to untreated hypothyroidism." — Diagnostic evaluation