enoxaparin
Pronunciation: /ɪˈnɒksəpærɪn/
Low molecular weight heparin used for anticoagulation in pediatric patients with thrombotic complications or central line protection.
Full Definition
Enoxaparin is a low molecular weight heparin (LMWH) derived from unfractionated heparin through controlled depolymerization. In pediatric hematology, it is commonly used for treatment and prevention of venous thromboembolism, particularly in patients with central venous catheters or inherited thrombophilia. Enoxaparin has more predictable pharmacokinetics than unfractionated heparin and typically requires less frequent monitoring. Dosing in children is weight-based and often requires anti-factor Xa level monitoring to ensure therapeutic ranges.
Usage
Usage note: Generic name preferred over brand name Lovenox. Include dosing units when mentioned.
In Context
- "The patient was started on enoxaparin 1 mg/kg subcutaneously twice daily for central line thrombosis." — Treatment plan
- "Anti-factor Xa levels should be monitored 4 hours after the third dose of enoxaparin." — Clinical protocol