flow cytometry
Laboratory technique essential for diagnosing and classifying pediatric leukemias and lymphomas.
Full Definition
Flow cytometry is an analytical technique that uses laser technology to analyze the physical and chemical characteristics of cells in suspension. In pediatric hematology, this method is indispensable for diagnosing acute leukemias, determining cell lineage (B-cell vs T-cell), monitoring minimal residual disease, and assessing immune function. The technique can rapidly analyze thousands of cells, providing detailed information about cell surface markers and intracellular proteins that guide treatment decisions.
Usage
Usage note: Two words. May be abbreviated as FC or referred to as FACS (fluorescence-activated cell sorting) in some contexts.
In Context
- "Flow cytometry confirmed B-cell acute lymphoblastic leukemia with characteristic CD19 and CD10 expression." — Pathology report
- "Minimal residual disease monitoring by flow cytometry showed excellent response to therapy." — Follow-up assessment