thrombocytopenia
Pronunciation: throm-bo-sigh-toe-PEE-nee-ah
Low platelet count in children that increases bleeding risk and may require treatment.
Full Definition
Thrombocytopenia is defined as a platelet count below the normal range for age, typically less than 150,000 per microliter. In pediatric hematology, this condition can result from decreased production (bone marrow disorders), increased destruction (immune thrombocytopenic purpura), or sequestration (enlarged spleen). The severity of bleeding risk correlates with platelet count, with counts below 20,000 requiring immediate medical attention and possible platelet transfusion.
Usage
Usage note: Single word, no hyphenation. Distinguish from thrombocytosis (elevated platelet count).
In Context
- "Severe thrombocytopenia with petechiae prompted immediate evaluation for ITP." — Emergency department note
- "Chemotherapy-induced thrombocytopenia required platelet transfusion support." — Oncology treatment summary