bronchiectasis
Pronunciation: brong-kee-EK-ta-sis
Abnormal widening and scarring of airways, often seen as a complication of recurrent respiratory infections in immunodeficient children.
Full Definition
Bronchiectasis is a chronic respiratory condition characterized by permanent dilation and scarring of the bronchi and bronchioles. In pediatric immunology, bronchiectasis frequently develops as a consequence of repeated pulmonary infections in children with primary immunodeficiencies, particularly antibody deficiencies. The condition results from chronic inflammation and infection that damages the airway walls, leading to impaired clearance of secretions and further susceptibility to infection. Early recognition and treatment of underlying immunodeficiency is crucial to prevent progression of bronchiectasis.
Usage
Usage note: Often misspelled as 'bronchectasis'; note the 'i' in the correct spelling.
In Context
- "High-resolution CT revealed early bronchiectasis in the lower lobes of this immunodeficient child." — Pulmonary imaging report
- "Prevention of bronchiectasis requires aggressive treatment of the underlying antibody deficiency." — Treatment planning document