neonatal HSV
Also written as: HSV — herpes simplex virus
Herpes simplex virus infection in newborns, potentially causing localized skin lesions, central nervous system disease, or disseminated infection.
Full Definition
Neonatal herpes simplex virus (HSV) infection is a serious condition affecting newborns, typically acquired during passage through an infected birth canal or through postnatal contact with infected individuals. The infection can manifest in three forms: localized skin, eye, and mouth disease; central nervous system disease; or disseminated disease affecting multiple organs. Symptoms may include vesicular skin lesions, seizures, lethargy, fever, or signs of sepsis. Early recognition and treatment with intravenous acyclovir are crucial for preventing severe complications including neurological sequelae and death. The condition requires high clinical suspicion, especially in neonates with unexplained fever, seizures, or vesicular lesions.
Usage
Usage note: Early recognition and treatment are critical; any vesicular lesions in neonates warrant immediate evaluation.
In Context
- "High-dose intravenous acyclovir was initiated for suspected neonatal HSV infection." — NICU progress note
- "The vesicular lesions on the newborn's scalp raised immediate concern for neonatal HSV." — Delivery room assessment