Omphalitis

Full Definition

Omphalitis is a serious neonatal infection involving the umbilical cord remnant and periumbilical tissues. It typically presents with erythema, swelling, and purulent discharge around the umbilicus, often with a foul odor. The infection can rapidly progress to necrotizing fasciitis or systemic sepsis, particularly in developing countries where it remains a significant cause of neonatal mortality. Staphylococcus aureus and group A streptococcus are common causative organisms.

Usage

Usage note: Requires urgent recognition and treatment to prevent life-threatening complications.

In Context

• "The neonate developed omphalitis with surrounding cellulitis requiring intravenous antibiotics." — Neonatal intensive care note
• "Purulent umbilical discharge and periumbilical erythema confirmed omphalitis." — Physical examination finding