Potter sequence
A constellation of fetal abnormalities resulting from severe oligohydramnios, often due to kidney malformations.
Full Definition
Potter sequence, also known as Potter syndrome, is a group of physical abnormalities that develop in a fetus as a result of severe oligohydramnios (decreased amniotic fluid). The condition is often caused by fetal kidney abnormalities such as renal agenesis, polycystic kidney disease, or severe kidney dysplasia that reduce fetal urine production. Characteristic features include distinctive facial abnormalities (Potter facies), limb deformities, growth restriction, and pulmonary hypoplasia. The pulmonary complications are often the most life-threatening aspect of the condition.
Usage
Usage note: Some sources prefer 'Potter sequence' over 'Potter syndrome' to emphasize the developmental cascade.
In Context
- "Prenatal ultrasound findings were consistent with Potter sequence secondary to bilateral renal agenesis." — Obstetric report
- "The neonate exhibited classic Potter facies with low-set ears and epicanthal folds." — Neonatal assessment