proteinuria
Pronunciation: pro-teen-YOO-ree-ah
Abnormal presence of protein in urine, often indicating kidney disease or dysfunction.
Full Definition
Proteinuria is the presence of excess protein in the urine, which normally contains only trace amounts. In pediatric nephrology, proteinuria is a key indicator of glomerular disease and is quantified through various methods including dipstick testing, spot urine protein-to-creatinine ratio, or 24-hour urine collection. Persistent proteinuria in children may indicate conditions such as nephrotic syndrome, glomerulonephritis, or hereditary nephritis. The degree of proteinuria helps classify disease severity and guide treatment decisions.
Usage
Usage note: Specify measurement method and reference ranges when documenting.
In Context
- "The child presented with significant proteinuria and edema suggestive of nephrotic syndrome." — Clinical assessment
- "Microalbuminuria was detected before the development of overt proteinuria." — Laboratory report