Shiga toxin-producing E. coli
Also written as: STEC — Shiga toxin-producing Escherichia coli
Bacterial pathogen that produces Shiga toxins, commonly causing hemolytic uremic syndrome in children.
Full Definition
Shiga toxin-producing Escherichia coli (STEC) is a bacterial pathogen that releases Shiga toxins, which damage the endothelium of glomerular capillaries and other blood vessels. The most common serotype is O157:H7, though non-O157 serotypes are increasingly recognized. STEC infection typically begins with bloody diarrhea and can progress to hemolytic uremic syndrome, particularly in children under 5 years of age. Early recognition is crucial as antibiotic treatment may increase toxin release and worsen outcomes.
Usage
Usage note: Often abbreviated as STEC in clinical documentation; distinguish from other pathogenic E. coli strains.
In Context
- "The microbiology report confirmed Shiga toxin-producing E. coli O157:H7 in the stool culture." — Laboratory report
- "Antibiotic therapy is contraindicated in suspected Shiga toxin-producing E. coli gastroenteritis." — Treatment guideline