ALCL
Also written as: ALCL — Anaplastic Large Cell Lymphoma
Anaplastic large cell lymphoma, a type of T-cell lymphoma that can occur in pediatric patients.
Full Definition
Anaplastic large cell lymphoma (ALCL) is a subtype of peripheral T-cell lymphoma characterized by large anaplastic cells that express CD30. In pediatric oncology, ALCL typically presents with lymph node enlargement and may involve extranodal sites. The ALK-positive variant has a better prognosis than ALK-negative forms, particularly in children and adolescents.
Usage
Usage note: Always specify ALK status when discussing ALCL.
In Context
- "The patient's ALCL showed strong ALK positivity by immunohistochemistry." — Pathology report
- "Pediatric ALCL generally has a more favorable outcome compared to adult cases." — Treatment protocol