What is Langerhans Cell Histiocytosis in Pediatric Pathology?

A clonal proliferative disorder of Langerhans cells characterised by the accumulation of CD1a- and CD207 (langerin)-positive histiocytes in various tissues, ranging from isolated bone lesions to multisystem disease.

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Pediatric Pathology Glossary

105 terms total — 1 showing — Last updated 15 Sep 2026

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Placental Site Nodule PSN

Advanced Technical IVT

A benign, hyalinised remnant of intermediate trophoblastic cells incidentally found in endometrial or cervical curettage specimens, representing a retained focus of implantation-site trophoblast.

15 Sep 2026

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Langerhans Cell Histiocytosis

Advanced Technical IVT

A clonal proliferative disorder of Langerhans cells characterised by the accumulation of CD1a- and CD207 (langerin)-posi...

LCH histiocytosis X (deprecated)

Technical Term Full entry →

Glossary terms, with category, difficulty and definition
Term	Category	Difficulty	Definition
Langerhans Cell Histiocytosis IVT	Technical Term	Advanced	A clonal proliferative disorder of Langerhans cells characterised by the accumul...

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Total terms 105

IVT eligible 101

Verified 0

basic 3

intermediate 25

advanced 43

professional 34