Pediatric Pathology Glossary
105 terms total — 24 showing — Last updated 15 Sep 2026
Placental Site Nodule PSN
A benign, hyalinised remnant of intermediate trophoblastic cells incidentally found in endometrial or cervical curettage specimens, representing a retained focus of implantation-site trophoblast.
ALTE
An apparent life-threatening event in infants, characterized by a combination of apnea, color change, and altered muscle...
Altman classification
A four-category surgical staging system for sacrococcygeal teratoma based on the proportion of tumour that is external v...
Alveolarisation
The developmental process by which saccules in the immature lung are subdivided into true alveoli, occurring primarily f...
anaplasia
A histological feature of tumour cells showing marked nuclear enlargement, hyperchromasia, and atypical mitotic figures,...
AT/RT
Abbreviation for atypical teratoid/rhabdoid tumour, an aggressive paediatric CNS malignancy defined by SMARCB1/INI1 loss...
atypical teratoid/rhabdoid tumour
A highly malignant embryonal CNS tumour of infancy and early childhood characterised by loss of SMARCB1 (INI1) or, rarel...
Autopsy Weight Standard
A set of reference organ-weight tables used in paediatric autopsy practice to assess whether individual organ weights ar...
Beckwith–Wiedemann syndrome
An overgrowth and tumour predisposition syndrome characterised by macroglossia, abdominal wall defects, visceromegaly, a...
biliary atresia
A neonatal cholestatic liver disease characterised by progressive obliteration or absence of the extrahepatic bile ducts...
blastema
Primitive tissue composed of undifferentiated cells that give rise to organs during embryonic development.
bronchopulmonary dysplasia
A chronic lung disease affecting premature infants who required mechanical ventilation and oxygen therapy.
Chorangiosis
A placental histological finding characterised by an abnormal increase in the number of capillaries within terminal vill...
chorioamnionitis
Inflammation of the fetal membranes and amniotic fluid, often due to bacterial infection during pregnancy.
Clear Cell Sarcoma of the Kidney
A malignant paediatric renal tumour characterised by a branching vascular pattern and bland cells with pale nuclei, noto...
COG
Children's Oncology Group; the primary North American cooperative clinical trials organisation for pediatric, adolescent...
congenital diaphragmatic hernia
A birth defect characterized by abnormal development of the diaphragm, allowing abdominal organs to herniate into the ch...
Congenital Lobar Overinflation
A neonatal pulmonary lesion characterised by progressive overdistension of one or more lobes due to a check-valve obstru...
Congenital Mesoblastic Nephroma
The most common renal tumour of the first three months of life, composed of spindle cells of fibroblastic or myofibrobla...
Congenital Pulmonary Airway Malformation
A spectrum of cystic and adenomatoid lesions of the lung arising from abnormal branching morphogenesis of the tracheobro...
CPAM
Congenital pulmonary airway malformation - a developmental lung lesion with cystic and solid components.
cystic nephroma
A benign, purely cystic renal neoplasm of early childhood associated with DICER1 mutations, characterised by multilocula...
Denys–Drash Syndrome
A WT1 germline mutation syndrome characterised by diffuse mesangial sclerosis leading to nephropathy, Wilms tumour predi...
desmoplastic small round cell tumour
A rare, highly aggressive soft-tissue sarcoma predominantly affecting adolescents and young adults, characterised by nes...
DICER1 syndrome
An autosomal dominant tumour predisposition syndrome caused by germline pathogenic variants in the DICER1 gene, associat...