bridging therapy
Temporary treatment used to maintain disease control while transitioning between long-term therapies.
Full Definition
Bridging therapy refers to the temporary use of medications to maintain disease control during transitions between long-term treatments in pediatric rheumatic diseases. This approach is commonly employed when switching from one disease-modifying antirheumatic drug to another, particularly when there may be a gap in therapeutic effect or when the new medication requires time to reach full efficacy. Common bridging therapies include short courses of corticosteroids, increased frequency of intra-articular injections, or temporary use of alternative DMARDs. The goal is to prevent disease flares while minimizing exposure to potentially harmful medications. Bridging therapy is particularly important in conditions where loss of disease control could lead to irreversible damage or functional impairment.
Usage
Usage note: Specify duration and rationale for bridging therapy in treatment plans.
In Context
- "A short course of prednisolone was used as bridging therapy while transitioning from adalimumab to rituximab." — Treatment transition plan
- "The bridging therapy successfully prevented disease flare during the medication washout period." — Clinical progress note