desmopressin
Pronunciation: des-mo-PRESS-in
Synthetic antidiuretic hormone used to treat nocturnal enuresis by reducing nighttime urine production.
Full Definition
Desmopressin is a synthetic analog of arginine vasopressin (antidiuretic hormone) commonly used in pediatric urology for managing nocturnal enuresis. It works by increasing water reabsorption in the kidneys, thereby reducing nighttime urine volume. Available in nasal spray, tablets, or sublingual forms, it's typically used as second-line therapy when behavioral interventions prove insufficient. Side effects can include water retention, hyponatremia, and headaches. Treatment response varies, and the medication's effects are temporary, with symptoms often returning upon discontinuation.
Usage
Usage note: Brand name DDAVP is often used interchangeably but generic name preferred in formal documentation.
In Context
- "Desmopressin therapy resulted in a significant reduction in wet nights from seven to two per week." — Treatment outcome assessment
- "Parents were counseled about potential water intoxication risks with desmopressin use." — Medication counseling note