VACTERL association
Pronunciation: VACK-ter-el
Also written as: VACTERL — Vertebral defects, Anal atresia, Cardiac defects, Tracheoesophageal fistula, Renal anomalies, Limb defects
Constellation of birth defects including vertebral, anal, cardiac, tracheoesophageal, renal, and limb anomalies often seen together.
Full Definition
A non-random association of congenital anomalies affecting multiple organ systems, where patients typically present with at least three of the characteristic defects. The acronym stands for Vertebral defects, Anal atresia, Cardiac defects, Tracheoesophageal fistula, Renal anomalies, and Limb defects. In pediatric urology, the renal and anal components are particularly relevant, as children may present with complex urogenital malformations requiring multidisciplinary care. The association is not a syndrome with a single genetic cause but rather a pattern of defects that occur together more frequently than expected by chance.
Usage
Usage note: Use all capitals for the acronym; some sources use VATER (without C and L components).
In Context
- "The newborn's multiple anomalies were consistent with VACTERL association requiring coordinated surgical planning." — Multidisciplinary consultation
- "Screening for VACTERL association components revealed additional cardiac and vertebral defects." — Diagnostic workup note