cordocentesis
Pronunciation: kor-do-sen-TEE-sis
A diagnostic procedure involving sampling of fetal blood directly from the umbilical cord. Also known as percutaneous umbilical blood sampling.
Full Definition
A prenatal diagnostic procedure in which fetal blood is obtained by inserting a needle through the maternal abdomen and uterus into the umbilical cord vessel, typically the umbilical vein. Also called percutaneous umbilical blood sampling (PUBS), this procedure is performed under ultrasound guidance, usually after 18 weeks of gestation. It allows for rapid chromosomal analysis, assessment of fetal anemia, evaluation of fetal infections, and monitoring of fetal acid-base status. The procedure carries risks including bleeding, infection, preterm labor, and fetal loss, so it is reserved for specific high-risk situations where the information cannot be obtained through less invasive means.
Usage
Usage note: PUBS is the preferred acronym in contemporary medical literature. Often confused with amniocentesis, which samples amniotic fluid rather than fetal blood.
In Context
- "Cordocentesis was performed to assess fetal anemia in this case of suspected parvovirus infection." — Maternal-fetal medicine consultation
- "The PUBS procedure revealed severe fetal acidosis requiring immediate intervention." — Procedure report