preeclampsia
Pronunciation: pree-ih-KLAMP-see-ah
Pregnancy complication characterized by high blood pressure and protein in urine, potentially progressing to seizures.
Full Definition
Preeclampsia is a serious pregnancy complication characterized by the development of hypertension (blood pressure ≥140/90 mmHg) and proteinuria (≥300 mg in 24-hour urine collection) after 20 weeks of gestation in previously normotensive women. The condition can affect multiple organ systems and may progress to eclampsia (seizures) or HELLP syndrome. Risk factors include first pregnancy, advanced maternal age, chronic hypertension, diabetes, and multiple gestations. Early recognition and management are crucial, as severe preeclampsia can lead to maternal and fetal complications including placental abruption, stroke, and intrauterine growth restriction.
Usage
Usage note: Distinguish from eclampsia (which includes seizures) and gestational hypertension (without proteinuria).
In Context
- "The patient developed severe preeclampsia at 34 weeks, requiring magnesium sulfate prophylaxis." — Obstetric consultation
- "Early signs of preeclampsia include persistent headaches and visual disturbances." — Patient education material