biofilm formation
Development of bacterial colonies on implant surfaces that can lead to chronic infection and implant failure.
Full Definition
Biofilm formation refers to the development of structured bacterial communities that adhere to implant surfaces and become encased in a protective extracellular matrix. In plastic surgery, biofilms commonly form on breast implants, tissue expanders, and other prosthetic materials. These bacterial colonies are highly resistant to antibiotics and the body's immune response, often leading to chronic infection, capsular contracture, or implant failure. Biofilm-related complications may require implant removal, antibiotic therapy, and delayed reconstruction. Prevention strategies include proper surgical technique, antibiotic irrigation, and textured surface modifications.
Usage
Usage note: Often associated with implant-related complications; distinguish from acute bacterial infection.
In Context
- "Chronic inflammation around the breast implant suggests possible biofilm formation requiring explantation." — Clinical assessment
- "Antibiotic pocket irrigation was performed to reduce the risk of biofilm formation on the tissue expander." — Operative report