oncotype score
Pronunciation: ON-ko-type
A numerical recurrence score derived from a multigene expression assay used to guide treatment decisions in breast cancer.
Full Definition
The Oncotype Score is a proprietary recurrence score ranging from 0-100 that quantifies the likelihood of distant recurrence in hormone receptor-positive, HER2-negative breast cancer. The score is calculated from the expression levels of 21 genes in tumor tissue and helps oncologists determine whether chemotherapy will benefit the patient in addition to hormone therapy. Lower scores typically indicate lower recurrence risk and may support omitting chemotherapy, while higher scores suggest greater benefit from chemotherapy.
Usage
Usage note: Always capitalize 'Oncotype' as it is a proprietary test name. The score is typically written without units.
In Context
- "The patient's Oncotype Score of 15 supported the decision to proceed with hormone therapy alone." — Treatment planning report
- "Oncotype scoring has become standard practice for intermediate-risk breast cancer patients." — Clinical guideline