Precision Oncology Glossary
100 terms total — 4 showing — Last updated 15 Sep 2026
tumor microenvironment TME
The cellular and molecular ecosystem surrounding cancer cells, including immune cells, stromal cells, blood vessels, and signaling molecules that influence tumor behavior and treatment response.
umbrella trial
A clinical trial design that tests multiple treatments within a single cancer type based on molecular subtypes.
variant allele frequency
The percentage of sequencing reads containing a specific genetic variant at a given genomic position. Critical for deter...
variant interpretation
The process of determining clinical significance and therapeutic relevance of genetic alterations identified through mol...
variant of unknown significance
A genetic alteration whose clinical impact and therapeutic implications remain unclear.