beta-hCG
Pronunciation: BAY-ta h-C-G
Beta subunit of human chorionic gonadotropin, a hormone measured in pregnancy testing and prenatal screening.
Full Definition
Beta-hCG (beta-human chorionic gonadotropin) is the beta subunit of the hormone human chorionic gonadotropin, produced by placental trophoblasts. It serves as the primary marker for pregnancy detection and is measured quantitatively in prenatal screening protocols. In first-trimester screening, free beta-hCG levels are assessed alongside PAPP-A and nuchal translucency to calculate risk for chromosomal abnormalities. Elevated levels may indicate multiple pregnancy, molar pregnancy, or increased risk of Down syndrome, while low levels may suggest miscarriage, ectopic pregnancy, or trisomy 18. Serial beta-hCG measurements are used to monitor pregnancy viability and progression.
Usage
Usage note: Note hyphenation and capitalization; distinguish from total hCG.
In Context
- "Free beta-hCG levels were elevated at 2.3 MoM in the first-trimester screen." — Laboratory report
- "Serial beta-hCG measurements confirmed appropriate rise consistent with viable intrauterine pregnancy." — Clinical documentation